Determinants of Circulating Soluble Leptin Receptor and Free Leptin Index in Indonesian Pre-Pubertal Obese Male Children: A Preliminary Cross-Sectional Study
نویسندگان
چکیده
منابع مشابه
Tracking of leptin, soluble leptin receptor, and the free leptin index during weight loss and regain in children.
OBJECTIVE To investigate changes in leptin and soluble leptin receptor (SLR) concentrations, and in the free leptin index (FLI) during weight loss and subsequent weight regain; and to ascertain whether these indices remain stable in the rank of the distribution in repeated measures (tracking) during perturbations of weight in obese children. DESIGN AND MEASUREMENTS In a longitudinal study, 11...
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Leptin (LEP) is associated with appetite regulation and metabolism. Concentration is linear with adiposity, suggesting LEP resistance. LEP circulates freely and bound with its soluble receptor (sOB-r); the ratio is the free leptin index (FLI), an index of leptin resistance; lower FLI suggests reduced biological action. Purpose. The aim was to determine the effect of changes in adipose tissue di...
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To investigate soluble leptin receptor (sLR) in plasma, specific anti-sLR monoclonal antibodies were developed. Western blot analysis and size exclusion fractionation demonstrated sLR in plasma with a molecular mass of approximately 180,000. Next to this, the presence of sLR-leptin complexes in plasma was confirmed. Using the developed monoclonal antibodies, a specific sLR ELISA was developed, ...
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Background/Objectives: Childhood obesity represents the most relevant nutritional disorder in our environment. This study examines the prevalence of metabolic syndrome in an obese pediatric population and its relation to serum Leptin concentrations. Subjects/Methods: A cross-sectional clinical and metabolic study was accomplished in a group of 106 obese children (47 males and 59 females). Patie...
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Background & aim: Government of Ethiopia is promoting institutional delivery despite the fact that there are a high number of home deliveries in the country mainly in hard-to-reach areas. Choice of institutional delivery is vital for the reduction of maternal and neonatal mortalities. The present study aimed to investigate the determinants of institutional delivery in ...
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ژورنال
عنوان ژورنال: Pediatric Gastroenterology, Hepatology & Nutrition
سال: 2020
ISSN: 2234-8646,2234-8840
DOI: 10.5223/pghn.2020.23.2.163